Mayor Marty Walsh, Red Sox brass, Boston public school students as well as the man known as Big Papi are scheduled to attend Thursday’s ceremony.
The mayor’s office says a street near Fenway Park currently known as Yawkey Way Extension will be renamed David Ortiz Drive.
Ortiz retired last season after a 20-year major league career, including 14 years in Boston. The designated hitter helped the Red Sox win three World Series championships, including their first in 86 years in 2004.
The Red Sox are scheduled to retire Ortiz’s No. 34 on Friday night.